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Text File  |  1987-10-07  |  694b  |  17 lines
  1.  
  2.          IN PATIENTS WITH RENAL IMPAIRMENT, ACYCLOVIR DOSAGE SHOULD BE
  3.          CAREFULLY ADJUSTED TO AVOID CNS TOXICITY (LETHARGY, SEIZURES,
  4.          HALLUCINATIONS, TREMOR, ETC).
  5.           
  6.          SOME CLINICIANS RECOMMEND THE FOLLOWING IV DOSAGE BASED ON
  7.          THE PATIENT'S CREATININE CLEARANCE:
  8.           
  9.            CREATININE CLEARANCE     DOSE        DOSING INTERVAL
  10.                (ML/MINUTE)
  11.           
  12.                 >50                5mg/kg             8 hours
  13.                 25-50              5mg/kg            12 hours
  14.                 10-25              5mg/kg            24 hours
  15.                 <10              2.5mg/kg            24 hours
  16.           
  17.